Thomas J Morgan Ph.D.
Director of Admissions, Associate Professor
Job Description
Tom Morgan is a member of the Principal Faculty in the School of Physician Assistant Practice. He is the Director of Admissions for the School of Physician Assistant Practice and the Course Director for the Physician Assistant Clinical Gross and Radiographic Anatomy course. Tom has worked as an industrial Research Scientist for Taxolog, Inc. in Tallahassee and also in the Experimental Therapeutics group at the Moffitt Cancer Center in Tampa where he conducted translational research in human cancer biology for the optimization and individualization of cancer treatment regimens. He has conducted research at the College of Medicine and The National High Magnetic Field Laboratory where he introduced stem cell isolation techniques to the Levenson lab and has expanded into using nanotechnology modified stem cells for potential therapies in glioma and traumatic brain injury. He has recently been working on nicotine-induced epigenetic modifications of paternal germline DNA in the Bhide lab.
Biosketch
July 2007-January 30, 2009. Research Scientist in Lead Investigation Group. Taxolog, Inc. Development and screening of novel chemotherapeutic and vascular disrupting agents.
March 2009-September 2009. Postdoctoral Fellow in Experimental Therapeutics and Translational Medicine, Moffitt Cancer Center, Tampa, FL. Identify and characterize responses of patient tumor samples to novel targeted therapies.
September 2009-December 2011. Postdoctoral Fellow in College of Medicine. Identify and characterize responses of glioma tumor samples to novel stem cell targeted therapies.
December 2011-December 2016. Assistant in Medicine, FSU College of Medicine.
January 2017-August 2018. Principal Faculty, Teaching Faculty I, School of Physician Assistant Practice, FSU College of Medicine.
August 2018-present. Principal Faculty, Assistant Professor, School of Physician Assistant Practice, FSU College of Medicine.
Education
Syracuse University, Syracuse, NY BS Biology 1984
The University of Texas at Austin, Austin, TX MA 1988 Biological Sciences
The University of Texas at Austin, Austin, TX PhD 1996 Biological Sciences
Service
Faculty advisor to The FSU Crew
Osher Lifelong Learning Institute Lecturer
Honors/Awards
Phi Kappa Phi National Honor Society
Memberships
Society for Neuroscience
Physician Assistant Education Association
Courses
Frontiers in Medicine (Chemotherapy and Drug Resistance Mechanisms. Stem cell therapies for Traumatic Brain Injury)
Gross Anatomy
Research Focus
Biomarkers of Drug Resistance in Glioblastoma
Use of Mesenchymal Stem Cells for Traumatic Brain Injury
Epigenetic Modifications of Paternal Germline DNA
Publications
Kline, K., Plante, L., Morgan, T.J.Jr., Sanders, B.G. "Chicken Transferrin Receptor Expression During Erythroid Differentiation and by Retrovirus Transformed Cells." Journal of Developmental and Comparative Immunology. 13: 231-52, 1989.
Kline, K., Cochran, G, Huggins, E.R., Morgan, T.J.Jr., Rao, A., Sanders, B.G. "Vitamin E Modulation of Retrovirus-Induced Immune Dysfunctions and Tumor Cell Proliferation." Annals of the New York Academy of Sciences. Proceedings of the Conference on Vitamin E: Biochemistry and Health Implications. A.T. Diplock, L.J. Machlin, L. Packer, and W.A. Pryor (eds). New York Academy of Sciences Press. N.Y., N.Y. 1989.
Kline, K., Rao, A., Romach, E.H., Kidao, S., Morgan, T.J.Jr.,Sanders, B.G. "Vitamin E Effects on Retrovirus-Induced Immune Dysfunctions." Annals of the New York Academy of Sciences. Proceedings of the Conference on Micronutrient Effects on Immune Function. R.K. Chandra and A. Bendich (eds). New York Academy of Sciences Press. N.Y.,N.Y. 1989.
Kline, K., Cochran, G, Huggins, E.R., Morgan, T.J.Jr., Rao, A., Sanders, B.G. "Vitamin E Inhibition of Tumor Cell Proliferation." Federal Proceedings. 3:A777, 1989.
Morgan, T.J.Jr., Lillehoj, H.S., Sanders, B.G., Kline, K. "Characterization and Developmental Expression of the Chicken B-G Heterodimer." Journal of Developmental and Comparative Immunology. 14: 425-37, 1990.
Kline, K., Bacon, L.D., Dietert, R.R., Lillehoj, H.S., Morgan, T.J.Jr., Sanders, B.G. "MHC Coded B-G Homodimer and Heterodimer Heterogeneity Among Different Chicken Lines." Journal of Heredity. 82: 31-6, 1991.
Kuang, G, Allen, J.R.., Baird, M.A., Lu Zhang, N., Morgan, T.J.Jr., Levenson, C.W., Davidson, M.W., and Zhu, L.Balance between Fluorescence Enhancement and Association Affinity in Fluorescent Heteroditopic Indicators for Imaging Zinc Ion in Living Cells Inorg. Chem., Article ASAP DOI: 10.1021/ic201728f: September 12, 2011
Schepkin, V.D., Calixto-Bejarano, F., Morgan, T.J.Jr., Gower-Winter, S.D., Ozambela, M.Jr., Levenson, C.W. In Vivo Magnetic Resonance Imaging of Sodium and Diffusion in Rat Glioma at 21.1 T. Magnetic Resonance in Medicine 67:1159–1166, 2012.
Schepkin, V.D., Morgan, T.J. Jr., Calixto-Bejarano, F., Petr L. Gor'kov, Petr L , William Brey, William., Chunqi Qian, Chungi., Gower-Winter, S.D., Ozambela, M.Jr., Levenson, C.W. Tumor drug resistance and sodium-diffusion MRI in rat glioma model. Proc. Intl. Soc. Mag. Reson. Med. 20 (2012)
Gower-Winter S.D., Corniola R.S., Morgan, T.J.Jr., Levenson, C.W. (2012) Zinc deficiency regulates hippocampal gene expression and impairs neuronal differentiation. Nutritional Neuroscience, Volume 16, Number 4, pp. 174-182(9) 2013.
Muroski, Megan., Morgan, T.J.Jr., Levenson, Cathy., Strouse, Geoffrey. A gold nanoparticle pentapeptide - gene chimera to induce targeted gene expression in mesenchymal stem cells. Journal of the American Chemical Society. DOI: 10.1021/ja505190q. 08 Sep, 2014
Rohit Seth, Rikki S. Corniola, Shannon D. Gower-Winter, Thomas J. Morgan Jr., Brian Bishop, Cathy W. Levenson. Zinc deficiency induces apoptosis via mitochondrial p53- and caspase-dependent pathways in human neuronal precursor cells. Journal of Trace Elements in Medicine and Biology. Volume 30, April 2015, Pages 59–65
McCarthy, D. M., Morgan, T., Lowe, S. E., Williamson, M. J., Spencer, T. J., Biederman, J., & Bhide, P. G. (2018). Nicotine exposure of male mice produces behavioral impairment in multiple generations of descendants. PLOS Biology. https://doi.org/10.1371/journal.pbio.2006497
Kate J. F. Carnevale, Megan E. Muroski, Parth N. Vakil, Megan E. Foley, Geoffry Laufersky, Rachael Kenworthy, Diego A. R. Zorio, Thomas J. Morgan, Jr., Cathy W. Levenson, and Geoffrey F. Strouse. Selective Uptake Into Drug Resistant Mammalian Cancer By Cell Penetrating Peptide-Mediated Delivery September 2018 Bioconjugate Chemistry 29(10) DOI: 10.1021/acs.bioconjchem.8b00429
Cathy W. Levenson, Thomas J. Morgan, Pamela D. Twigg, Timothy M. Logan, Victor D. Schepkin. Use of MRI, metabolomic, and genomic biomarkers to identify mechanisms of chemoresistance in glioma. Cancer Drug Resist 2019;2:862-876. 10.20517/cdr.2019.18
McCarthy, D.M., Lowe, S.E., Morgan, T.J. et al. Transgenerational transmission of behavioral phenotypes produced by exposure of male mice to saccharin and nicotine. Sci Rep 10, 11974 (2020). https://doi.org/10.1038/s41598-020-68883-6
Tom Morgan is a member of the Principal Faculty in the School of Physician Assistant Practice. He is the Director of Admissions for the School of Physician Assistant Practice and the Course Director for the Physician Assistant Clinical Gross and Radiographic Anatomy course. Tom has worked as an industrial Research Scientist for Taxolog, Inc. in Tallahassee and also in the Experimental Therapeutics group at the Moffitt Cancer Center in Tampa where he conducted translational research in human cancer biology for the optimization and individualization of cancer treatment regimens. He has conducted research at the College of Medicine and The National High Magnetic Field Laboratory where he introduced stem cell isolation techniques to the Levenson lab and has expanded into using nanotechnology modified stem cells for potential therapies in glioma and traumatic brain injury. He has recently been working on nicotine-induced epigenetic modifications of paternal germline DNA in the Bhide lab.
July 2007-January 30, 2009. Research Scientist in Lead Investigation Group. Taxolog, Inc. Development and screening of novel chemotherapeutic and vascular disrupting agents.
March 2009-September 2009. Postdoctoral Fellow in Experimental Therapeutics and Translational Medicine, Moffitt Cancer Center, Tampa, FL. Identify and characterize responses of patient tumor samples to novel targeted therapies.
September 2009-December 2011. Postdoctoral Fellow in College of Medicine. Identify and characterize responses of glioma tumor samples to novel stem cell targeted therapies.
December 2011-December 2016. Assistant in Medicine, FSU College of Medicine.
January 2017-August 2018. Principal Faculty, Teaching Faculty I, School of Physician Assistant Practice, FSU College of Medicine.
August 2018-present. Principal Faculty, Assistant Professor, School of Physician Assistant Practice, FSU College of Medicine.
Syracuse University, Syracuse, NY BS Biology 1984
The University of Texas at Austin, Austin, TX MA 1988 Biological Sciences
The University of Texas at Austin, Austin, TX PhD 1996 Biological Sciences
Faculty advisor to The FSU Crew
Osher Lifelong Learning Institute Lecturer
Phi Kappa Phi National Honor Society
Society for Neuroscience
Physician Assistant Education Association
Frontiers in Medicine (Chemotherapy and Drug Resistance Mechanisms. Stem cell therapies for Traumatic Brain Injury)
Gross Anatomy
Biomarkers of Drug Resistance in Glioblastoma
Use of Mesenchymal Stem Cells for Traumatic Brain Injury
Epigenetic Modifications of Paternal Germline DNA
Kline, K., Plante, L., Morgan, T.J.Jr., Sanders, B.G. "Chicken Transferrin Receptor Expression During Erythroid Differentiation and by Retrovirus Transformed Cells." Journal of Developmental and Comparative Immunology. 13: 231-52, 1989.
Kline, K., Cochran, G, Huggins, E.R., Morgan, T.J.Jr., Rao, A., Sanders, B.G. "Vitamin E Modulation of Retrovirus-Induced Immune Dysfunctions and Tumor Cell Proliferation." Annals of the New York Academy of Sciences. Proceedings of the Conference on Vitamin E: Biochemistry and Health Implications. A.T. Diplock, L.J. Machlin, L. Packer, and W.A. Pryor (eds). New York Academy of Sciences Press. N.Y., N.Y. 1989.
Kline, K., Rao, A., Romach, E.H., Kidao, S., Morgan, T.J.Jr.,Sanders, B.G. "Vitamin E Effects on Retrovirus-Induced Immune Dysfunctions." Annals of the New York Academy of Sciences. Proceedings of the Conference on Micronutrient Effects on Immune Function. R.K. Chandra and A. Bendich (eds). New York Academy of Sciences Press. N.Y.,N.Y. 1989.
Kline, K., Cochran, G, Huggins, E.R., Morgan, T.J.Jr., Rao, A., Sanders, B.G. "Vitamin E Inhibition of Tumor Cell Proliferation." Federal Proceedings. 3:A777, 1989.
Morgan, T.J.Jr., Lillehoj, H.S., Sanders, B.G., Kline, K. "Characterization and Developmental Expression of the Chicken B-G Heterodimer." Journal of Developmental and Comparative Immunology. 14: 425-37, 1990.
Kline, K., Bacon, L.D., Dietert, R.R., Lillehoj, H.S., Morgan, T.J.Jr., Sanders, B.G. "MHC Coded B-G Homodimer and Heterodimer Heterogeneity Among Different Chicken Lines." Journal of Heredity. 82: 31-6, 1991.
Kuang, G, Allen, J.R.., Baird, M.A., Lu Zhang, N., Morgan, T.J.Jr., Levenson, C.W., Davidson, M.W., and Zhu, L.Balance between Fluorescence Enhancement and Association Affinity in Fluorescent Heteroditopic Indicators for Imaging Zinc Ion in Living Cells Inorg. Chem., Article ASAP DOI: 10.1021/ic201728f: September 12, 2011
Schepkin, V.D., Calixto-Bejarano, F., Morgan, T.J.Jr., Gower-Winter, S.D., Ozambela, M.Jr., Levenson, C.W. In Vivo Magnetic Resonance Imaging of Sodium and Diffusion in Rat Glioma at 21.1 T. Magnetic Resonance in Medicine 67:1159–1166, 2012.
Schepkin, V.D., Morgan, T.J. Jr., Calixto-Bejarano, F., Petr L. Gor'kov, Petr L , William Brey, William., Chunqi Qian, Chungi., Gower-Winter, S.D., Ozambela, M.Jr., Levenson, C.W. Tumor drug resistance and sodium-diffusion MRI in rat glioma model. Proc. Intl. Soc. Mag. Reson. Med. 20 (2012)
Gower-Winter S.D., Corniola R.S., Morgan, T.J.Jr., Levenson, C.W. (2012) Zinc deficiency regulates hippocampal gene expression and impairs neuronal differentiation. Nutritional Neuroscience, Volume 16, Number 4, pp. 174-182(9) 2013.
Muroski, Megan., Morgan, T.J.Jr., Levenson, Cathy., Strouse, Geoffrey. A gold nanoparticle pentapeptide - gene chimera to induce targeted gene expression in mesenchymal stem cells. Journal of the American Chemical Society. DOI: 10.1021/ja505190q. 08 Sep, 2014
Rohit Seth, Rikki S. Corniola, Shannon D. Gower-Winter, Thomas J. Morgan Jr., Brian Bishop, Cathy W. Levenson. Zinc deficiency induces apoptosis via mitochondrial p53- and caspase-dependent pathways in human neuronal precursor cells. Journal of Trace Elements in Medicine and Biology. Volume 30, April 2015, Pages 59–65
McCarthy, D. M., Morgan, T., Lowe, S. E., Williamson, M. J., Spencer, T. J., Biederman, J., & Bhide, P. G. (2018). Nicotine exposure of male mice produces behavioral impairment in multiple generations of descendants. PLOS Biology. https://doi.org/10.1371/journal.pbio.2006497
Kate J. F. Carnevale, Megan E. Muroski, Parth N. Vakil, Megan E. Foley, Geoffry Laufersky, Rachael Kenworthy, Diego A. R. Zorio, Thomas J. Morgan, Jr., Cathy W. Levenson, and Geoffrey F. Strouse. Selective Uptake Into Drug Resistant Mammalian Cancer By Cell Penetrating Peptide-Mediated Delivery September 2018 Bioconjugate Chemistry 29(10) DOI: 10.1021/acs.bioconjchem.8b00429
Cathy W. Levenson, Thomas J. Morgan, Pamela D. Twigg, Timothy M. Logan, Victor D. Schepkin. Use of MRI, metabolomic, and genomic biomarkers to identify mechanisms of chemoresistance in glioma. Cancer Drug Resist 2019;2:862-876. 10.20517/cdr.2019.18
McCarthy, D.M., Lowe, S.E., Morgan, T.J. et al. Transgenerational transmission of behavioral phenotypes produced by exposure of male mice to saccharin and nicotine. Sci Rep 10, 11974 (2020). https://doi.org/10.1038/s41598-020-68883-6