Pradeep Bhide Ph.D.

Professor, Jim and Betty Ann Rodgers Eminent Scholar Chair of Developmental Neuroscience, Director, Center for Brain Repair

Main Campus

Dr. Pradeep G. Bhide is the Jim and Betty Ann Rodgers Eminent Scholar Chair of Developmental Neuroscience and the director of the Center for Brain Repair at the Florida State University College of Medicine.

Dr. Bhide received his degree in Veterinary Medicine from Veterinary College, Bangalore, India, and a Ph.D. in neuroscience from the University of Aberdeen, Scotland. He undertook postdoctoral training in developmental neurobiology at University College, London; Yale University; and Massachusetts General Hospital and Harvard Medical School.

Administrative Responsibilities
Director, Interdepartmental Neuroscience Center, Massachusetts General Hospital, Boston, MA (2003-11)
Vice Chair for Neurology Research, Massachusetts General Hospital, Boston, MA (2007-11)
Director, Center for Brain Repair, FSU College of Medicine (2011-present)

Editorial Boards
Senior Editor, Developmental Neuroscience (2009-present)

Editorial Board - Developmental Neuroscience (2005-present)

Editorial Board: Current Neuropharmacology (2009-present)

Associate Editor, Frontiers in Neurogenesis (2022-present)

Editorial Board: Neurotoxicology and Teratology (2022-present)

MRC (UK) Research Assistantship

Wellcome Trust (UK) Fellowship

Charles A. King Trust Fellowship, Boston, MA

Montreal Neurological Institute Young Investigator Award, Montreal, Canada

Partners in Excellence - Leadership and Innovation Award Massachusetts General Hospital, Boston, MA

Outstanding Senior Faculty Researcher Award Florida State University Faculty Council, Tallahassee, FL

Society for Neuroscience

Society for Birth Defects Research and Prevention

Developmental Neurotoxicology Society

American Professional Society for ADHD and Related Disorders

Neuroscience: CNS and Behavior (BMS 6046C)

Foundations of Medicine 2

Musculoskeletal and Integumentary Systems

Biomedical Innovation and Entrepreneurship

The research in the Bhide laboratory focuses on developmental neurological and psychiatric conditions including ADHD and early-onset generalized dystonia. Another area of research focus is the neurological and cognitive effects of prenatal and early postnatal exposure to prescription and illicit drugs.

Current research projects include examination of the role of dopamine receptor activation in the developing brain; the effects of prenatal exposure to cocaine, nicotine and non-nutritive sweetners on the development of the brain and behavior; and the developmental origins of the movement disorder generalized dystonia.

Dr. Bhide’s laboratory employs a variety of technologies including microscopy, histology, biochemistry and molecular biology, cell and tissue culture, neuropharmacology, and behavioral analysis.

Research Group

Research Faculty
Deirdre McCarthy, B.S.

Graduate Students
Sara Jones, B.S.

Amber Parnell, B.S.

Mia Trupiano, B.S.

Undergraduate Students
Diego Figueroa

Daniel Zuniga

Jada Llerena

Jones, S.K., McCarthy, D.M., Vied, C., Stanwood, G.D., Schatschneider, C., Bhide, P.G. 2022. Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala. Proc. Natl. Acad. Sci. USA. 119 (14): e2213120119.

McCarthy, D.M., Zhang, L., Wilkes, B.J., Vaillancourt, D.E., Biederman, J., Bhide, P.G., 2022. Nicotine and the developing brain: Insights from preclinical models. Pharmacol Biochem Behav, Feb 14;173355. doi: 10.1016/j.pbb.2022.173355.

Zhang, L., Levenson, C.W., Salazar, V.C., Biederman, J., Zafonte, R., Bhide, P.G., 2022. Repetitive Mild Traumatic Brain Injury in an Awake, Unanesthetized Mouse Model of Perinatal Nicotine Exposure Produces Transient Novelty-Seeking and Depression-Like Behaviors. J Neurotrauma. DOI 10.1089/neu.2021.0268

McCarthy DM, Bhide PG. Heritable consequences of paternal nicotine exposure: From phenomena to mechanisms. Biology of reproduction. 2021; Epub 2021/06/15. doi: 10.1093/biolre/ioab116. PubMed PMID: 34126634.

Zhang L, Levenson CW, Salazar VC, McCarthy DM, Biederman J, Zafonte R, Bhide PG. "Repetitive Mild Traumatic Brain Injury in a Perinatal Nicotine Exposure Mouse Model of Attention Deficit Hyperactivity Disorder." Dev Neurosci. 2021;43(1):1-10. PubMed PMID: 33849015.

Zhang L, McCarthy DM, Eskow Jaunarajs KL, Biederman J, Spencer TJ, Bhide PG. "Frontal Cortical Monoamine Release, Attention, and Working Memory in a Perinatal Nicotine Exposure Mouse Model Following Kappa Opioid Receptor Antagonism." Cerebral Cortex. 2021;31(1):483-96. doi: 10.1093/cercor/bhaa238

Martin MM, McCarthy DM, Schatschneider C, Trupiano MX, Jones SK, Kalluri A, Bhide PG. "Effects of Developmental Nicotine Exposure on Frontal Cortical GABA-to-Non-GABA Neuron Ratio and Novelty-Seeking Behavior." Cereb Cortex. 2020;30:1830-42. PubMed PMID: 31599922

McCarthy DM, Lowe SE, Morgan TJ, Cannon EN, Biederman J, Spencer TJ, Bhide PG. "Transgenerational transmission of behavioral phenotypes produced by exposure of male mice to saccharin and nicotine." Sci Rep. 2020;10(1):11974. PubMed PMID: 32686722; PMCID: PMC7371742.

McCarthy DM, Morgan TJ, Jr., Lowe SE, Williamson MJ, Spencer TJ, Biederman J, Bhide, PG (2018). "Nicotine exposure of male mice produces behavioral impairment in multiple generations of descendants." PLoS Biol. 16:e2006497.

Zhang L, Spencer TJ, Biederman J, Bhide PG (2018). "Attention and working memory deficits in a perinatal nicotine exposure mouse model." PLoS One. 13:e0198064.

Spencer TJ, Bhide P, Zhu J, Faraone SV, Fitzgerald M, Yule AM, Uchida M, Spencer AE, Hall AM, Koster AJ, Feinberg L, Kassabian S, Storch B, Biederman J. "The Mixed Opioid Receptor Antagonist Naltrexone Mitigates Stimulant-Induced Euphoria: A Double-Blind, Placebo-Controlled Trial of Naltrexone." J Clin Psychiatry. 2018;79(2):17m11609. doi: 10.4088/JCP.17m11609. PubMed PMID: 29617066.

Spencer TJ, Bhide P, Zhu J, Faraone SV, Fitzgerald M, Yule AM, Uchida M, Spencer AE, Hall AM, Koster AJ, Biederman J. "Opiate Antagonists Do Not Interfere With the Clinical Benefits of Stimulants in ADHD: A Double-Blind, Placebo-Controlled Trial of the Mixed Opioid Receptor Antagonist Naltrexone." J Clin Psychiatry. 2017. doi: 10.4088/JCP.16m11012. PubMed PMID: 28640990.