Deirdre Mary McCarthy
Research Faculty II
Job Description
Deirdre Mc Carthy is Research Faculty in the Department of Biomedical Sciences, Assistant Director of The Florida Institute for Pediatric Rare Diseases and member of The Center for Brain Repair. Her research interests focus on developmental and behavioral neuroscience.
Biosketch
Education
Deirdre received her BSc. in Biochemistry from University College Cork, Ireland. She trained at Massachusettes General Hospital and Harvard Medical School with Dr. Pradeep Bhide and joined the faculty at FSU, College of Medicine in 2011.
Service
CoM Wellness Committee June 2024- present
FSU, CoM Equipment Committee (2022-2023)
FSU Animal Care and Use Committee (2015–2020)
FSU Exercise in Medicine-On Campus (January 2025- present)
Honors/Awards
Tris Pharma Award, Tris Pharma (2021, 2022)
Outstanding Junior Faculty Investigator Award, FSU College of Medicine (2017)
Best Presentation Award, 2017 APSARD Annual Meeting (2017)
Memberships
Professional Women's Nexus
Society for Neuroscience
American Professional Society of ADHD and Related Disorders
Developmental Neurotoxicology Society
Courses
Special Topics in Biomedical Sciences
Professional and Career Development for Biomedical Sciences
Frontiers in Medicine
Neuroscience Methods
Research Focus
Environmental and genetic influences on the developing brain.
Development of innovative tools for diagnosis and treatment of neurodevelopmental disorders
Publications
Publications can be found at:
https://www.ncbi.nlm.nih.gov/myncbi/deirdre.mccarthy.1/bibliography/public/
Recent publications include:
Trupiano, M., McCarthy, DM., Bhide, PG (2026) Motivational subdomains in Neurodevelopmental Disorders: A Heuristic Circuit Framework for Translational Validation. Biol Psychiatry Cogn Neurosci Neuroimaging. doi: 10.1016/j.bpsc.2026.03.006. PMID: 41856475
Parnell, A., Truiano, M.X., McCarthy, D.M., Schatschneider, C., Bhide, P.G. (2025) Nicotine in e-cigarette aerosol reduces GABA neuron migration via the α7 nicotinic acetylcholine receptor. Sci Rep 15, 35635. https://doi.org/10.1038/s41598-025-19504-7. PMCID: PMC12518607 PMID: 41083506.\
McCarthy, D.M., Vied, C., Trupiano, M.X., Canekeratne, A.J., Wang, Y., Schatschneider, C., Bhide, P.G. Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 knockout mice. Front. Behav. Neurosci. doi: https://doi.org/10.3389/fnbeh.2024.1458502
Espinoza, P., Cheng, M., Ng, C., de la Cruz, D., Wasson, E.D.,, McCarthy, D.M., Bhide, P.G., Maguire, C.A., and Santoscoy, M.C. Metabolic engineering improves transduction efficiency and downstream vector isolation by altering the lipid composition of extracellular vesicle-enclosed AAV. BioRxiv. doi: https://doi.org/10.1101/2024.08.16.608303
Jones SK, McCarthy DM, Vied C, Stanwood GD, Schatschneider C, Bhide PG.
Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2213120119. doi: 10.1073/pnas.2213120119. Epub 2022 Dec 2. PMID: 36459641; PMCID: PMC9894161.
Martin MM, Graham DL, McCarthy DM, Bhide PG, Stanwood GD. Cocaine-induced neurodevelopmental deficits and underlying mechanisms. Birth Defects Res C Embryo Today. 2016 Jun;108(2):147-73. doi: 10.1002/bdrc.21132. PMID: 27345015; PMCID: PMC5538582.
Jones SK, McCarthy DM, Stanwood GD, Schatschneider C, Bhide PG. Learning and memory deficits produced by aspartame are heritable via the paternal lineage. Sci Rep. 2023 Aug 31;13(1):14326. doi: 10.1038/s41598-023-41213-2. PMID:37652922; PMCID: PMC10471780.
McCarthy DM, Bhide PG. Heritable consequences of paternal nicotine exposure: from phenomena to mechanisms†. Biol Reprod. 2021 Sep 14;105(3):632-643. doi:10.1093/biolre/ioab116. PMID: 34126634; PMCID: PMC8444703.
McCarthy DM, Zhang L, Wilkes BJ, Vaillancourt DE, Biederman J, Bhide PG. Nicotine and the developing brain: Insights from preclinical models. Pharmacol Biochem Behav. 2022 Mar;214:173355. doi: 10.1016/j.pbb.2022.173355. Epub 2022
Feb 14. PMID: 35176350; PMCID: PMC9063417.
McCarthy DM, Kabir ZD, Bhide PG, Kosofsky BE. Effects of prenatal exposure to cocaine on brain structure and function. Prog Brain Res. 2014;211:277-89. doi:10.1016/B978-0-444-63425-2.00012-X. PMID: 24968785.
McCarthy DM, Brown AN, Bhide PG. Regulation of BDNF expression by cocaine. Yale J Biol Med. 2012 Dec;85(4):437-46. Epub 2012 Dec 13. PMID: 23239946; PMCID: PMC3516887.
Jones SK, McCarthy DM, Vied C, Stanwood GD, Schatschneider C, Bhide PG. Reply to Charles V. Vorhees: Aspartame and anxiety-like behavior. Proc Natl Acad Sci USA. 2023 Jun 13;120(24):e2304679120. doi: 10.1073/pnas.2304679120. Epub 2023 Jun 5. PMID: 37276421; PMCID: PMC10268190.
Biederman J, Fitzgerald M, Spencer TJ, Bhide PG, McCarthy DM, Woodworth KY, Saunders A, Faraone SV. Is Paternal Smoking at Conception a Risk for ADHD? A Controlled Study in Youth With and Without ADHD. J Atten Disord. 2020
Sep;24(11):1493-1496. doi: 10.1177/1087054717690809. Epub 2017 Feb 2. PMID:28152645.
Pavlock S, McCarthy DM, Kesarwani A, Jean-Pierre P, Bhide PG. Hippocampal neuroinflammation following combined exposure to cyclophosphamide and naproxen in ovariectomized mice. Int J Neurosci. 2023 Feb;133(2):159-168. doi:
10.1080/00207454.2021.1896508. Epub 2021 Mar 10. PMID: 33635748.
McCarthy DM, Spencer TJ, Bhide PG. Preclinical Models of Attention Deficit Hyperactivity Disorder: Neurobiology, Drug Discovery, and Beyond. J Atten Disord. 2024 Mar;28(5):880-894. doi: 10.1177/10870547231215286. Epub 2023 Dec
12. PMID: 38084074.
Martin MM, McCarthy DM, Schatschneider C, Trupiano MX, Jones SK, Kalluri A, Bhide PG. Effects of Developmental Nicotine Exposure on Frontal Cortical GABA-to-Non-GABA Neuron Ratio and Novelty-Seeking Behavior. Cereb Cortex. 2020 Mar14;30(3):1830-1842. doi: 10.1093/cercor/bhz207. PMID: 31599922; PMCID:
PMC7305802.
Lee GS, Graham DL, Noble BL, Trammell TS, McCarthy DM, Anderson LR, Rubinstein M, Bhide PG, Stanwood GD. Behavioral and Neuroanatomical Consequences of Cell-Type Specific Loss of Dopamine D2 Receptors in the Mouse CerebralCortex. Front Behav Neurosci. 2022 Jan 13;15:815713. doi:10.3389/fnbeh.2021.815713. PMID: 35095443; PMCID: PMC8793809.
McCarthy DM, Lowe SE, Morgan TJ, Cannon EN, Biederman J, Spencer TJ, Bhide PG. Transgenerational transmission of behavioral phenotypes produced by exposureof male mice to saccharin and nicotine. Sci Rep. 2020 Jul 20;10(1):11974. doi:10.1038/s41598-020-68883-6. PMID: 32686722; PMCID: PMC7371742.
Additional Information
Bhide Lab Members
Principal Investigator: Pradeep Bhide Ph.D.
Mia Trupiano, Ph.D.
Undergraduate Students
Jacob Trainor
Sindu Bilapati
Medical Students
Kenzie Taylor Luckett
Deirdre Mc Carthy is Research Faculty in the Department of Biomedical Sciences, Assistant Director of The Florida Institute for Pediatric Rare Diseases and member of The Center for Brain Repair. Her research interests focus on developmental and behavioral neuroscience.
Deirdre received her BSc. in Biochemistry from University College Cork, Ireland. She trained at Massachusettes General Hospital and Harvard Medical School with Dr. Pradeep Bhide and joined the faculty at FSU, College of Medicine in 2011.
CoM Wellness Committee June 2024- present
FSU, CoM Equipment Committee (2022-2023)
FSU Animal Care and Use Committee (2015–2020)
FSU Exercise in Medicine-On Campus (January 2025- present)
Tris Pharma Award, Tris Pharma (2021, 2022)
Outstanding Junior Faculty Investigator Award, FSU College of Medicine (2017)
Best Presentation Award, 2017 APSARD Annual Meeting (2017)
Professional Women's Nexus
Society for Neuroscience
American Professional Society of ADHD and Related Disorders
Developmental Neurotoxicology Society
Special Topics in Biomedical Sciences
Professional and Career Development for Biomedical Sciences
Frontiers in Medicine
Neuroscience Methods
Environmental and genetic influences on the developing brain.
Development of innovative tools for diagnosis and treatment of neurodevelopmental disorders
Publications can be found at:
https://www.ncbi.nlm.nih.gov/myncbi/deirdre.mccarthy.1/bibliography/public/
Recent publications include:
Trupiano, M., McCarthy, DM., Bhide, PG (2026) Motivational subdomains in Neurodevelopmental Disorders: A Heuristic Circuit Framework for Translational Validation. Biol Psychiatry Cogn Neurosci Neuroimaging. doi: 10.1016/j.bpsc.2026.03.006. PMID: 41856475
Parnell, A., Truiano, M.X., McCarthy, D.M., Schatschneider, C., Bhide, P.G. (2025) Nicotine in e-cigarette aerosol reduces GABA neuron migration via the α7 nicotinic acetylcholine receptor. Sci Rep 15, 35635. https://doi.org/10.1038/s41598-025-19504-7. PMCID: PMC12518607 PMID: 41083506.\
McCarthy, D.M., Vied, C., Trupiano, M.X., Canekeratne, A.J., Wang, Y., Schatschneider, C., Bhide, P.G. Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 knockout mice. Front. Behav. Neurosci. doi: https://doi.org/10.3389/fnbeh.2024.1458502
Espinoza, P., Cheng, M., Ng, C., de la Cruz, D., Wasson, E.D.,, McCarthy, D.M., Bhide, P.G., Maguire, C.A., and Santoscoy, M.C. Metabolic engineering improves transduction efficiency and downstream vector isolation by altering the lipid composition of extracellular vesicle-enclosed AAV. BioRxiv. doi: https://doi.org/10.1101/2024.08.16.608303
Jones SK, McCarthy DM, Vied C, Stanwood GD, Schatschneider C, Bhide PG.
Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2213120119. doi: 10.1073/pnas.2213120119. Epub 2022 Dec 2. PMID: 36459641; PMCID: PMC9894161.
Martin MM, Graham DL, McCarthy DM, Bhide PG, Stanwood GD. Cocaine-induced neurodevelopmental deficits and underlying mechanisms. Birth Defects Res C Embryo Today. 2016 Jun;108(2):147-73. doi: 10.1002/bdrc.21132. PMID: 27345015; PMCID: PMC5538582.
Jones SK, McCarthy DM, Stanwood GD, Schatschneider C, Bhide PG. Learning and memory deficits produced by aspartame are heritable via the paternal lineage. Sci Rep. 2023 Aug 31;13(1):14326. doi: 10.1038/s41598-023-41213-2. PMID:37652922; PMCID: PMC10471780.
McCarthy DM, Bhide PG. Heritable consequences of paternal nicotine exposure: from phenomena to mechanisms†. Biol Reprod. 2021 Sep 14;105(3):632-643. doi:10.1093/biolre/ioab116. PMID: 34126634; PMCID: PMC8444703.
McCarthy DM, Zhang L, Wilkes BJ, Vaillancourt DE, Biederman J, Bhide PG. Nicotine and the developing brain: Insights from preclinical models. Pharmacol Biochem Behav. 2022 Mar;214:173355. doi: 10.1016/j.pbb.2022.173355. Epub 2022
Feb 14. PMID: 35176350; PMCID: PMC9063417.
McCarthy DM, Kabir ZD, Bhide PG, Kosofsky BE. Effects of prenatal exposure to cocaine on brain structure and function. Prog Brain Res. 2014;211:277-89. doi:10.1016/B978-0-444-63425-2.00012-X. PMID: 24968785.
McCarthy DM, Brown AN, Bhide PG. Regulation of BDNF expression by cocaine. Yale J Biol Med. 2012 Dec;85(4):437-46. Epub 2012 Dec 13. PMID: 23239946; PMCID: PMC3516887.
Jones SK, McCarthy DM, Vied C, Stanwood GD, Schatschneider C, Bhide PG. Reply to Charles V. Vorhees: Aspartame and anxiety-like behavior. Proc Natl Acad Sci USA. 2023 Jun 13;120(24):e2304679120. doi: 10.1073/pnas.2304679120. Epub 2023 Jun 5. PMID: 37276421; PMCID: PMC10268190.
Biederman J, Fitzgerald M, Spencer TJ, Bhide PG, McCarthy DM, Woodworth KY, Saunders A, Faraone SV. Is Paternal Smoking at Conception a Risk for ADHD? A Controlled Study in Youth With and Without ADHD. J Atten Disord. 2020
Sep;24(11):1493-1496. doi: 10.1177/1087054717690809. Epub 2017 Feb 2. PMID:28152645.
Pavlock S, McCarthy DM, Kesarwani A, Jean-Pierre P, Bhide PG. Hippocampal neuroinflammation following combined exposure to cyclophosphamide and naproxen in ovariectomized mice. Int J Neurosci. 2023 Feb;133(2):159-168. doi:
10.1080/00207454.2021.1896508. Epub 2021 Mar 10. PMID: 33635748.
McCarthy DM, Spencer TJ, Bhide PG. Preclinical Models of Attention Deficit Hyperactivity Disorder: Neurobiology, Drug Discovery, and Beyond. J Atten Disord. 2024 Mar;28(5):880-894. doi: 10.1177/10870547231215286. Epub 2023 Dec
12. PMID: 38084074.
Martin MM, McCarthy DM, Schatschneider C, Trupiano MX, Jones SK, Kalluri A, Bhide PG. Effects of Developmental Nicotine Exposure on Frontal Cortical GABA-to-Non-GABA Neuron Ratio and Novelty-Seeking Behavior. Cereb Cortex. 2020 Mar14;30(3):1830-1842. doi: 10.1093/cercor/bhz207. PMID: 31599922; PMCID:
PMC7305802.
Lee GS, Graham DL, Noble BL, Trammell TS, McCarthy DM, Anderson LR, Rubinstein M, Bhide PG, Stanwood GD. Behavioral and Neuroanatomical Consequences of Cell-Type Specific Loss of Dopamine D2 Receptors in the Mouse CerebralCortex. Front Behav Neurosci. 2022 Jan 13;15:815713. doi:10.3389/fnbeh.2021.815713. PMID: 35095443; PMCID: PMC8793809.
McCarthy DM, Lowe SE, Morgan TJ, Cannon EN, Biederman J, Spencer TJ, Bhide PG. Transgenerational transmission of behavioral phenotypes produced by exposureof male mice to saccharin and nicotine. Sci Rep. 2020 Jul 20;10(1):11974. doi:10.1038/s41598-020-68883-6. PMID: 32686722; PMCID: PMC7371742.
Bhide Lab Members
Principal Investigator: Pradeep Bhide Ph.D.
Mia Trupiano, Ph.D.
Undergraduate Students
Jacob Trainor
Sindu Bilapati
Medical Students
Kenzie Taylor Luckett